Insulin resistance: old or obese?
نویسندگان
چکیده
منابع مشابه
Prevalence of insulin resistance in obese adolescence
Childhood obesity is a global health problem with several metabolic and cardiovascular complications. The prevalence of childhood and adolescent obesity is differed in each country with several affecting factors. Insulin resistance as one common feature of obesity is known to have a link with the risk of diabetes type 2 and cardiovascular complication. Insulin resistance is also a basic mechani...
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Multiple causes can drive the development of insulin resistance in children and adolescents, such as sedentary behavior, specific dietary elements, and genetic factors, yet the most common cause in this age group is obesity. Obesity is defined in general as an excess adipose tissue. Adipose tissue may be stored in several depots which differ in their localization, anatomical structure, as well ...
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OBJECTIVE To evaluate the presence of insulin resistance and its association with other metabolic abnormalities in obese children and adolescents. METHODS Retrospective study of 220 children and adolescents aged 5-14 years. Anthropometric measurements were performed (weight, height, and waist circumference) and clinical (gender, age, pubertal stage, and degree of obesity) and biochemical (glu...
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To determine if structural changes in forearm resistance vessels are associated with insulin resistance, we evaluated the relation between minimum forearm vascular resistance and insulin resistance in 95 obese adolescents before and after weight loss. Insulin resistance was assessed by fasting insulin levels and sum of insulin values after an oral glucose tolerance test in all 95 subjects and w...
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Subclinical systemic inflammation is a hallmark of obesity and insulin resistance. The results obtained from a number of experimental studies suggest that targeting different components of the inflammatory machinery may result in the improvement of the metabolic phenotype. Unsaturated fatty acids exert antiinflammatory activity through several distinct mechanisms. Here, we tested the capacity o...
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ژورنال
عنوان ژورنال: Nature Immunology
سال: 2015
ISSN: 1529-2908,1529-2916
DOI: 10.1038/ni.3360